MMP-9/10-IN-2

MMP-9/10-IN-2

• UNSPSC Description: MMP-9/10-IN-2 (compound 6e) is a potent inhibitor of MMP10 and MMP9, with IC50 of 0.076 μM for MMP10, and 93.18% inhibition at 0.5 μM for MMP9. MMP-9/10-IN-2 plays an important role in anti-tumor[1].
• Target Antigen: MMP
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mmp-9-10-in-2.html
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: O=C(C1=CC=C(NC(N=C(O)N2)=NC2=O)C=C1)NC3=CC=C(C(F)(F)F)C=C3
• Molecular Weight: 391.30
• References & Citations: [1]Hosam H Khalil, et al. Chemosensitization of non-small cell lung cancer to sorafenib via non-hydroxamate s-triazinedione-based MMP-9/10 inhibitors. Bioorg Chem. 2024 Mar:144:107155.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported