Eupatorin

• Description:

  Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly (ADP-ribose) polymerase cleavage[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H301

• Target:

  Apoptosis

• Type:

  Natural Products

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/eupatorin.html

• Purity:

  99.97

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=CC(OC)=C(OC)C(O)=C13

• Molecular Formula:

  C18H16O7

• Molecular Weight:

  344.32

• Precautions:

  H301

• References & Citations:

  [1]Estévez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway. PLoS One. 2014 Nov 12;9 (11) :e112536.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [855-96-9]