Eupatorin

• Description :

  Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly (ADP-ribose) polymerase cleavage[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  Apoptosis

• Type :

  Natural Products

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/eupatorin.html

• Purity :

  99.97

• Solubility :

  DMSO : 250 mg/mL (ultrasonic)

• Smiles :

  O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=CC(OC)=C(OC)C(O)=C13

• Molecular Formula :

  C18H16O7

• Molecular Weight :

  344.32

• Precautions :

  H301

• References & Citations :

  [1]Estévez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway. PLoS One. 2014 Nov 12;9 (11) :e112536.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [855-96-9]