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Eupatilin

CAT: 0804-HY-N0783-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0783-01Size:10 mg
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Description
Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi, is a PPARĪ± agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.
CAS Number
[22368-21-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; PPAR
Type
Natural Products
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Eupatilin.html
Purity
98.90
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C13
Molecular Formula
C18H16O7
Molecular Weight
344.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Jung Y, et al. Eupatilin, an activator of PPARĪ±, inhibits the development of oxazolone-induced atopic dermatitis symptoms in Balb/c mice. Biochem Biophys Res Commun. 2018 Feb 5;496 (2) :508-514.|[2]Jung Y, et al. Eupatilin with PPARĪ± agonistic effects inhibits TNFĪ±-induced MMP signaling in HaCaT cells. Biochem Biophys Res Commun. 2017 Nov 4;493 (1) :220-226.|[3]Du L, et al. Eupatilin prevents H2O2-induced oxidative stress and apoptosis in human retinal pigment epithelial cells. Biomed Pharmacother. 2017 Jan;85:136-140.
Shipping Conditions
Room Temperature
Storage Conditions
-20Ā°C, 3 years; 4Ā°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
PPARĪ±

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