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CDC25B-IN-1

CAT: 0804-HY-126246-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126246-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase, with a Ki of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phase[1].
CAS Number
2374831-10-2
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc25b-in-1.html
Purity
98.12
Solubility
DMSO : 100 mg/mL (ultrasonic)|Ethanol : 50 mg/mL (ultrasonic)
Smiles
COC1=CC2=CC=CC=C2C(NC3=CC=CC(C(OCC)=O)=C3)=C1
Molecular Formula
C20H19NO3
Molecular Weight
321.37
References & Citations
[1]Cerchia C, et al. Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines. J Med Chem. 2019 Aug 8;62 (15) :7089-7110.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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