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CDC20-IN-1

CAT: 0804-HY-161257Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161257Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDC20-IN-1 (Compound E1) is a specific inhibitor of CDC20 and can be used in triple-negative breast cancer research. CDC20-IN-1 can induce autophagy in cancer cells and inhibit MDA-MB-231 cell proliferation, with an IC50 value of 1.43 μM[1].
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc20-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(CC)NC(C(Cl)(Cl)Cl)N(C=N1)C2=C1C(NC3=CC(OC)=C(OC)C(OC)=C3)=NC(N)=N2
Molecular Formula
C19H22Cl3N7O4
Molecular Weight
518.78
References & Citations
[1]Zhao SF, et al. Design, synthesis and biological evaluation of CDC20 inhibitors for treatment of triple-negative breast cancer. Eur J Med Chem. 2024 Feb 8;268:116204.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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