SANT-1

CAT: 0804-HY-100224-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100224-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling. SANT-1 shows IC50s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 assay, respectively[1].
CAS Number
[304909-07-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Hedgehog; Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SANT-1.html
Purity
99.87
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=C(/C=N/N2CCN(CC3=CC=CC=C3)CC2)C(C)=NN1C4=CC=CC=C4
Molecular Formula
C23H27N5
Molecular Weight
373.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Chen JK, et al. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A. 2002 Oct 29;99 (22) :14071-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-107408-01SANT 2
HY-122017Methoxy-SANT-2
HY-W096178B-01Silica sand, 1-2mm
HY-P991434SAN-300
HY-W096178CSilica sand, 2-7mm
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-149536TWIK-1/TREK-1-IN-1
HY-W160628S1,1,1-Trimethoxypropane-d5

Alternative Products

CatalogName
MBS386099-01SANT-1
A13095-50SANT-1 50mg
A13095-5SANT-1 5mg
A13095-10SANT-1 10mg
A13095-100SANT-1 100mg
A13095-2SANT-1 2mg
A13095-25SANT-1 25mg
465852-01SANT-2

Popular Products