MK-7845

• UNSPSC Description:

  MK-7845 is a reversible covalent SARS-CoV-2 3CL protease inhibitor with an IC50 of 8.7 nM[1].

• Target Antigen:

  SARS-CoV

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mk-7845.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CNC(C([C@@H](NC([C@@H]1[C@H]2CCC[C@H]2CN1C([C@H](C(C)(C)C)NC(OC)=O)=O)=O)CCC(F)(F)C)=O)=O

• Molecular Weight:

  516.58

• References & Citations:

  [1]Valerie W Shurtleff, et al. Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J Med Chem. 2024 Feb 16.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2952554-69-5