Dimethyl-bisphenol A

• Description :

  Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. Dimethyl-bisphenol A can decrease Vegfa mRNA expression[1].

• Product Name Alternative :

  DMBPA

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/dimethyl-bisphenol-a.html

• Concentration :

  10mM

• Purity :

  99.78

• Solubility :

  DMSO : ≥ 100 mg/mL

• Smiles :

  COC(C=C1)=CC=C1C(C)(C)C(C=C2)=CC=C2OC

• Molecular Formula :

  C17H20O2

• Molecular Weight :

  256.34

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Diana P Trebec-Reynolds, et al. VEGF-A expression in osteoclasts is regulated by NF-kappaB induction of HIF-1alpha. J Cell Biochem. 2010 May 15;110 (2) :343-51.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1568-83-8]