Bisphenol C

CAT: 0804-HY-W114419-01Size: 10 gDry Ice: NoHazardous: No
CAT#:0804-HY-W114419-01Size:10 g
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Bisphenol C is an estrogen receptor-α (ERα) agonist and an ERβ antagonist, with IC50 values of 2.65 nM for ERα and 1.94 nM for ERβ. Bisphenol C is a material of manufacturing polyester polymers like polycarbonate, is widely used in daily items like water bottles, food packaging, textile and so on[1][2][3].
CAS Number
[79-97-0]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Estrogen Receptor/ERR; mTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bisphenol-c.html
Purity
98.0
Smiles
CC1=CC(=CC=C1O)C(C)(C)C2=CC=C(C(=C2)C)O
Molecular Formula
C17H20O2
Molecular Weight
256.34
Precautions
H315, H319, H335
References & Citations
[1]Xiaohui Liu, et al. Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding. PLoS One. 2021 Feb 9;16 (2) :e0246583.|[2]Su K, et al. Bisphenol C Induces Cardiac Developmental Defects by Disrupting m6A Homeostasis. Environ Sci Technol. 2024 Oct 1;58 (39) :17259-17269. |[3]Liu J, et al. Bisphenol C induces developmental defects in liver and intestine through mTOR signaling in zebrafish (Danio rerio) . Chemosphere. 2023 May;322:138195.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα

Popular Products