Colesevelam (hydrochloride)
CAT:
804-HY-106539-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Colesevelam (hydrochloride)
- CAS Number: 182815-44-7
- UNSPSC Description: Colesevelam (hydrochloride) is a bile acid sequestrant that bind bile acids in the gut. Colesevelam (hydrochloride) inhibits bile acid reabsorption, leading to increased bile acid synthesis and reduced cholesterol levels in patients with cholestatic pruritus and Crohn’s disease.
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease; Cancer
- Assay Protocol: https://www.medchemexpress.com/colesevelam-hydrochloride.html
- Purity: 95.0
- Solubility: 10 mM in DMSO
- Smiles: [Colesevelam (hydrochloride)]
- Molecular Weight: 3694.64
- References & Citations: [1]Potthoff MJ, Potts A, He T, et al. Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice. Am J Physiol Gastrointest Liver Physiol. 2013;304(4):G371-G380. |[2]Cabré N, Duan Y, Llorente C, et al. Colesevelam Reduces Ethanol-Induced Liver Steatosis in Humanized Gnotobiotic Mice. Cells. 2021;10(6):1496.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched