Cirazoline (hydrochloride)
CAT:
804-HY-101300-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cirazoline (hydrochloride)
- CAS Number: 40600-13-3
- UNSPSC Description: Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full?α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM)[1].
- Target Antigen: Adenosine Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/cirazoline-hydrochloride.html
- Purity: 99.65
- Solubility: H2O : 33.33 mg/mL (ultrasonic)
- Smiles: [H]Cl.C1(COC2=CC=CC=C2C3CC3)=NCCN1
- Molecular Weight: 252.74
- References & Citations: [1]Doze VA, et al. alpha(1A)- and alpha(1B)-adrenergic receptors differentially modulate antidepressant-like behaviorin the mouse.Brain Res. 2009 Aug 18;1285:148-57.|[2]Suzana Assad Kahn , et al. The Anti-Hypertensive Drug Prazosin Inhibits Glioblastoma Growth via the PKCδ-dependent Inhibition of the AKT Pathway. EMBO Mol Med. 2016 May 2;8(5):511-26.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported