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Corynoline (Standard)

CAT: 0804-HY-N0826RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N0826RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Corynoline (Standard) is the analytical standard of Corynoline. This product is intended for research and analytical applications. Corynoline is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM[1]. Corynoline exhibits anti-inflammatory activity by activating Nrf2[2].
CAS Number
[18797-79-0]
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Keap1-Nrf2; Reference Standards
Type
Reference Standards
Related Pathways
Neuronal Signaling; NF-κB; Others
Field of Research
Inflammation/Immunology; Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/corynoline-standard.html
Smiles
C[C@@]1(C(C=CC2=C3OCO2)=C3CN4C)[C@@]4([H])C(C=C(OCO5)C5=C6)=C6C[C@@H]1O
Molecular Formula
C21H21NO5
Molecular Weight
367.40
References & Citations
[1]Kim DK. Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase. Arch Pharm Res. 2002 Dec;25 (6) :817-9.|[2]Liu B, et al. Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS) -Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2. Inflammation. 2018 Oct;41 (5) :1640-1647.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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