PROZ rabbit pAb

CAT: 0855-ES20310-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES20310-01Size:50 µL
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Background
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Description
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],
UniProt
P22891
Swiss Prot
P22891
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human PROZ AA range: 141-190
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
Vitamin K-dependent protein Z
Gene ID (Human)
8858

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