6-Hydroxyindole

• Description :

  6-Hydroxyindole is a biochemical reagent. 6-hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor, and is elevated plasma of the renal failure patients[1].

• CAS Number :

  [2380-86-1]

• UNSPSC :

  12352200

• Hazard Statement :

  H302, H317, H318, H411

• Target :

  Biochemical Assay Reagents; Endogenous Metabolite

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/6-hydroxyindole.html

• Concentration :

  10mM

• Purity :

  99.99

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  OC1=CC2=C(C=C1)C=CN2

• Molecular Formula :

  C8H7NO

• Molecular Weight :

  133.15

• Precautions :

  H302, H317, H318, H411

• References & Citations :

  [1]Masuo Y, et al. 6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients. Drug Metab Pharmacokinet. 2020 Dec;35 (6) :555-562.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported