DOCK4 rabbit pAb

DOCK4 rabbit pAb

• Description: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008],
• Gene ID: 9732
• UniProt: Q8N1I0
• Cellular Locus: Cell membrane. Cell projection. Cytoplasm, cytosol. Colocalizes with EPHA2, RHOG and CTTN/cortactin at the tip of protrusions in migrating cells..
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthesized peptide derived from human DOCK4 AA range: 533-583
• Clonality: Polyclonal
• Validated Applications: WB
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1：500-2000
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.