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SC5AC rabbit pAb

CAT: 0855-ES13190-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13190-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+) -coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+) -coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]) .[supplied by OMIM, Dec 2008]
Description
Normal blood lactate is maintained at about 1. 5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al. 2007 [PubMed 17692818]). [supplied by OMIM, Dec 2008],
UniProt
Q1EHB4
Swiss Prot
Q1EHB4
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human SC5AC AA range: 84-134
Target
SC5AC
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Apical cell membrane ; Multi-pass membrane protein . Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity) . .
Gene ID (Human)
159963

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