Products for Research Use Only
RegisterLogin

GuaB-IN-1

CAT: 0804-HY-169916Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-169916Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GuaB-IN-1 (Compound 15) exhibits high potency against M.tb with a MIC value of 0.25 μM. GuaB-IN-1 has a favorable 28% hERG inhibition profile at 10 μM. GuaB-IN-1 is promising for research of tuberculosis[1].
UNSPSC
12352005
Target
Bacterial; Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Anti-infection; Vitamin D Related/Nuclear Receptor
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/guab-in-1.html
Smiles
C[C@H](C1=NN=CC(N2N=C(Cl)C=C2)=C1)OC(C=C3)=CC(N4CCOCC4=C5)=C3C5=O
Molecular Formula
C21H18ClN5O3
Molecular Weight
423.85
References & Citations
[1]Zhou Y, et al. Discovery of potent dihydro-oxazinoquinolinone inhibitors of GuaB for the treatment of tuberculosis. Bioorg Med Chem Lett. 2024 Nov 12:130026.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-179301GuaB-IN-2
HY-W145516-01Guar gum
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-149536TWIK-1/TREK-1-IN-1
HY-W160628S1,1,1-Trimethoxypropane-d5
HY-133630-011-Bromo-1,1-dichloroacetone
HY-1336291,1,1,3-Tetrachloroacetone
HY-W881439-011- (1,1-Dimethylethyl) tridecanedioate

Alternative Products

CatalogName
T203122-01GuaB-IN-1
GTR17982255GuaB Antibody
MBS9017647Rabbit anti-Shigella flexneri guaB Polyclonal Antibody
MBS1456921-01Recombinant Staphylococcus aureus Inosine-5'-monophosphate dehydrogenase (guaB)
MBS1475930-01Recombinant Staphylococcus epidermidis Inosine-5'-monophosphate dehydrogenase (guaB)
MBS1480521-01Recombinant Chlorobium tepidum Inosine-5'-monophosphate dehydrogenase (guaB)
MBS1381954-01Recombinant Bacillus halodurans Inosine-5'-monophosphate dehydrogenase (guaB)
MBS1296693-01Recombinant Thermoplasma acidophilum Inosine-5'-monophosphate dehydrogenase (guaB)
MBS1172357-01Recombinant Aquifex aeolicus Inosine-5'-monophosphate dehydrogenase (guaB)
MBS1072268-01Recombinant Pyrococcus horikoshii Inosine-5'-monophosphate dehydrogenase (guaB)

Popular Products