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ISAM-140

CAT: 0804-HY-111082-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111082-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ISAM-140 (22b) is a potent and highly selective A2B adenosine receptor antagonist with a Ki of 3.49 nM[1].
CAS Number
932191-62-3
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/isam-140.html
Purity
99.85
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C)N=C2NC3=CC=CC=C3N2C1C4=CC=CO4)OC(C)C
Molecular Formula
C19H19N3O3
Molecular Weight
337.37
Precautions
H315, H319, H335
References & Citations
[1]El Maatougui A, et al. Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes. J Med Chem. 2016 Mar 10;59 (5) :1967-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A2B receptor (A2BR)

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