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1-Monomyristin

CAT: 0804-HY-N2512-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2512-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM) . 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].
CAS Number
589-68-4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Bacterial; Endogenous Metabolite; FAAH; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/1-monomyristin.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC(OCC(O)CO)=O
Molecular Formula
C17H34O4
Molecular Weight
302.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Shimada H, et al. Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens) . J Nat Prod. 1997 Apr;60 (4) :417-8.|[2]Vandevoorde S, et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochem Biophys Res Commun. 2005 Nov 11;337 (1) :104-9.|[3]Jumina, et al. Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents. Molecules. 2018 Nov 29;23 (12) . pii: E3141
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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