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Formoterol-d6

CAT: 0804-HY-B0010S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0010S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Formoterol-d6 is the deuterium labeled Formoterol. Formoterol ((±) Formoterol) is a potent, selective and long-acting β2-adrenoceptor agonist[1].
CAS Number
1020719-45-2
Product Name Alternative
(±) Formoterol-d6
UNSPSC
12352005
Hazard Statement
H315-H317-H319-H335-H336-H362-H373
Target
Adrenergic Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Endocrinology
Solubility
10 mM in DMSO
Smiles
C(CNC(C(C1=CC=C(OC)C=C1)([2H])[2H])(C([2H])([2H])[2H])[2H])(O)C2=CC(NC=O)=C(O)C=C2
Molecular Formula
C₁₉H₁₈D₆N₂O₄
Molecular Weight
350.44
Precautions
P260-P261-P263-P264-P270-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Arun JJ, Lodha R, Kabra SK. Bronchodilatory effect of inhaled budesonide/formoterol and budesonide/salbutamol in acute asthma: a double-blind, randomized controlled trial.BMC Pediatr. 2012 Mar 7;12:21.|[3]Cope S, Kraemer M, Zhang J, Efficacy of indacaterol 75 μg versus fixed-dose combinations of formoterol-budesonide or salmeterol-fluticasone for COPD: a network meta-analysis. Int J Chron Obstruct Pulmon Dis. 2012;7:415-20.|[4]Tacon CE, Newton R, Proud D, Rhinovirus-induced MMP-9 expression is dependent on Fra-1, which is modulated by formoterol and dexamethasone. J Immunol. 2012 May 1;188 (9) :4621-30.|[5]Zhong N, Lin J, Mehta P, Real-life effectiveness of budesonide/formoterol maintenance and reliever therapy in asthma patients across Asia: SMARTASIA study. BMC Pulm Med. 2013 Apr 4;13 (1) :22.|[6]Shinkai N, Takasuna K, Takayama S. Tocolytic activity of formoterol against premature delivery in mice. J Pharm Pharmacol. 2002 Dec;54 (12) :1637-43.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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