TGFβ1-IN-1
CAT:
804-HY-151427-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TGFβ1-IN-1
- CAS Number: 2348795-14-0
- UNSPSC Description: TGFβ1-IN-1 (compound 42) is a potent, orally active TGF-β1 inhibitor. TGFβ1-IN-1 inhibits the upregulation of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in liver fibrosis disease studies[1].
- Target Antigen: TGF-β Receptor
- Type: Reference compound
- Related Pathways: TGF-beta/Smad
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/tgfβ1-in-1.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NC1CCCC1)C2=CC=CC(NC(/C=C/C3=CC=C(OC)C=C3)=O)=C2
- Molecular Weight: 364.44
- References & Citations: [1]Lin Yue, et al. Discovery and evaluation of phenacrylanilide derivatives as novel potential anti-liver fibrosis agents. Eur J Med Chem. 2022 Nov 15;242:114685.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported