KCNQ1 activator-1

KCNQ1 activator-1

• CAS Number: 1008671-38-2
• UNSPSC Description: KCNQ1 activator-1 (compound 3) is a potent activator of KCNQ1 channel. KCNQ1 activator-1 has the potential for the research of long QT syndrome (LQTS)[1].
• Target Antigen: Potassium Channel
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/kcnq1-activator-1.html
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: O=C(C1N(S(=O)(C2=CC=CC=C2)=O)CCCC1)NC3=NC(C4=CC=C(OC)C=C4)=CS3
• Molecular Weight: 457.57
• References & Citations: [1]Mattmann ME, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported