Estradiol 3-sulfate 17-glucuronide (potassium)

• UNSPSC Description:

  Estradiol 3-sulfate 17-glucuronide potassium is metabolite of estradiol. Estradiol 3-sulfate 17-glucuronide potassium inhibits multidrug resistance protein (MRP) mediated 17β -Estradiol 17-(β -D-Glucuronide) transport with a Ki of 22 μM[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/estradiol-3-sulfate-17-glucuronide-potassium.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@](CC[C@@H]2O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O[K])=O)([H])[C@@]4([H])[C@@](CC1)([H])C5=CC=C(OS(=O)(O[K])=O)C=C5CC4

• Molecular Weight:

  604.75

• References & Citations:

  [1]Loe DW, et al., ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids. J Biol Chem. 1996 Apr 19;271(16):9683-9.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  10392-35-5