Estradiol 17-(β-D-Glucuronide) (sodium)

• UNSPSC Description:

  Estradiol 17-(β-D-Glucuronide) sodium, a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Endocrinology; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/estradiol-17-β-d-glucuronide-sodium.html

• Purity:

  99.46

• Solubility:

  DMSO : 50 mg/mL (ultrasonic;adjust pH to 3 with 1 M HCL)

• Smiles:

  C[C@@]12[C@](CC[C@@H]2O[C@]3([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O[Na])=O)([H])[C@@]4([H])[C@](C5=C(C=C(O)C=C5)CC4)([H])CC1

• Molecular Weight:

  470.49

• References & Citations:

  [1]Kinbara S, et al. Improvement of estradiol-17 beta-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats. Scand J Gastroenterol. 1997;32(9):947-952.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  15087-02-2