Human Epidermal Growth Factor Receptor

• Description:

  Human Epidermal Growth Factor Receptor_x000D_ Catalog number: B2010377_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human Epidermal Growth Factor Receptor expressed in Sf9 insect cells. This protein acts as a member of the tyrosine kinase receptors family and plays important roles in cell growth and differentiation._x000D_ Storage: -20C_x000D_ Keywords: rHuEGFR, His; ErbB1; HER1; ERBB_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Rajaram P, Chandra P, Ticku S, Pallavi BK, Rudresh KB, Mansabdar P. Epidermal_x000D_ growth factor receptor: Role in human cancer. Indian J Dent Res. 2017 Nov-_x000D_ Dec;28(6):687-694._x000D_ _x000D_ 2: Liu X, Wang P, Zhang C, Ma Z. Epidermal growth factor receptor (EGFR): A_x000D_ rising star in the era of precision medicine of lung cancer. Oncotarget. 2017_x000D_ Jul 25;8(30):50209-50220._x000D_ _x000D_ 3: Sabbah DA, Hajjo R, Sweidan K. Review on Epidermal Growth Factor Receptor_x000D_ (EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR_x000D_ Inhibitors. Curr Top Med Chem. 2020;20(10):815-834._x000D_ _x000D_ 4: Kobayashi Y, Mitsudomi T. Not all epidermal growth factor receptor mutations_x000D_ in lung cancer are created equal: Perspectives for individualized treatment_x000D_ strategy. Cancer Sci. 2016 Sep;107(9):1179-86._x000D_ _x000D_ 5: Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J. A structural perspective on_x000D_ the regulation of the epidermal growth factor receptor. Annu Rev Biochem._x000D_ 2015;84:739-64._x000D_ _x000D_ 6: Gan HK, Cvrljevic AN, Johns TG. The epidermal growth factor receptor variant_x000D_ III (EGFRvIII): where wild things are altered. FEBS J. 2013 Nov;280(21):5350-70._x000D_ _x000D_ 7: Schneider MR, Wolf E. The epidermal growth factor receptor ligands at a_x000D_ glance. J Cell Physiol. 2009 Mar;218(3):460-6._x000D_ _x000D_ 8: Voldborg BR, Damstrup L, Spang-Thomsen M, Poulsen HS. Epidermal growth factor_x000D_ receptor (EGFR) and EGFR mutations, function and possible role in clinical_x000D_ trials. Ann Oncol. 1997 Dec;8(12):1197-206._x000D_ 9: Tomas A, Futter CE, Eden ER. EGF receptor trafficking: consequences for_x000D_ signaling and cancer. Trends Cell Biol. 2014 Jan;24(1):26-34. doi:_x000D_ 10.1016/j.tcb.2013.11.002. Epub 2013 Nov 29. PMID: 24295852; PMCID: PMC3884125._x000D_ _x000D_ Products Related to Human Epidermal Growth Factor Receptor : Proteins

• Short Description:

  Catalog Number: B2010377 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5