6'-Sialyllactose

• Description:

  6'-Sialyllactose promotes the growth of beneficial bacteria (such as Bifidobacterium and lactobacillus) and inhibits the proliferation of harmful bacteria. 6'-Sialyllactose exhibits anti-inflammatory and anti-angiogenic activities. 6'-Sialyllactose promotes the muscle health[1][2][3][4].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319

• Target:

  Akt; Bacterial; ERK; VEGFR

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; MAPK/ERK Pathway; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/6-sialyllactose.html

• Purity:

  99.51

• Solubility:

  H2O : ≥ 50 mg/mL

• Smiles:

  O=C[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]([C@@H]([C@H]([C@H]1O)O)O)O[C@@H]1CO[C@]2(O[C@@]([C@@H]([C@H](C2)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C(O)=O

• Molecular Formula:

  C23H39NO19

• Molecular Weight:

  633.55

• Precautions:

  H315, H319

• References & Citations:

  [1]MariarosariaMarotta, et al. The predominant milk oligosaccharide 6′-sialyllactose reduces the internalisation of Pseudomonas aeruginosa in human pneumocytes. Journal of Functional Foods Volume 6, January 2014, Pages 367-373.|[2]Tarr AJ, et al., The prebiotics 3'Sialyllactose and 6'Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the gut-brain axis. Brain Behav Immun. 2015 Nov;50:166-177.|[3]Park EJ, et al., 6'-Sialyllactose Enhances Exercise Performance via Increased Muscle Mass and Strength. Nutrients. 2024 Aug 7;16 (16) :2600.|[4]Kim EY, et al., 6-sialyllactose ameliorates dihydrotestosterone-induced benign prostatic hyperplasia through suppressing VEGF-mediated angiogenesis. BMB Rep. 2019 Sep;52 (9) :560-565.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [35890-39-2]