REST rabbit pAb

• Gene ID:

  5978

• UniProt:

  Q13127

• Cellular Locus:

  Nucleus. Cytoplasm. Colocalizes with ZFP90 in the nucleus (By similarity). In response to hypoxia, there is a more pronounced increase in levels in the nucleus as compared to the cytoplasm (PubMed:27531581). In aging neurons, increased levels in the nucleus as compared to the cytoplasm (PubMed:24670762, PubMed:30684677)..; [Isoform 2]: Cytoplasm.; [Isoform 3]: Nucleus.; [Isoform 4]: Cytoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human REST AA range: 593-643

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB

• Validated Applications:

  WB

• Stability:

  -20°C / 1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-2000

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Nucleus . Cytoplasm . Colocalizes with ZFP90 in the nucleus (By similarity) . In response to hypoxia, there is a more pronounced increase in levels in the nucleus as compared to the cytoplasm (PubMed:27531581) . In aging neurons, increased levels in the nucleus as compared to the cytoplasm (PubMed:24670762, PubMed:30684677) . .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Nucleus .; [Isoform 4]: Cytoplasm .

• Gene ID (Human):

  5978

• SwissProt (Human):

  Q13127