Kp7-6

• UNSPSC Description:

  Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury[1][2].

• Target Antigen:

  Apoptosis

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/kp7-6.html

• Purity:

  99.77

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N1)=O)CCC(O)=O)=O)CC(O)=O)=O)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(O)=O)CC3=CC=C(C=C3)O)=O)=O)CC4=CC=CC=C4)[C@@H]1CC5=CN=CN5

• Molecular Weight:

  1077.15

• References & Citations:

  [1]Zhang S, et al. Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes. 2008 Feb;57(2):348-56.|[2]Hasegawa A, et al. Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6599-604.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  629628-53-1