Adenosine-d2

• Description:

  Adenosine-d2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio

• Product Name Alternative:

  Adenine riboside-d2; D-Adenosine-d2

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis; Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Metabolic Disease

• Purity:

  99.56

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  NC1=C2C(N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)C([2H])([2H])O)O)O)=NC=N1

• Molecular Formula:

  C10H11D2N5O4

• Molecular Weight:

  269.25

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [2]Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98 (3) :1591-1625.; Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ.|[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [82741-17-1]