Products for Research Use Only
RegisterLogin

MRZ 2-514

CAT: 0804-HY-101620-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101620-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.
CAS Number
202808-11-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/MRZ_2-514.html
Purity
95.08
Solubility
10 mM in DMSO
Smiles
O=C1NNC(C2=C1C=C3C=C(Br)C=CC3=[N+]2[O-])=O
Molecular Formula
C11H6BrN3O3
Molecular Weight
308.09
Precautions
H302, H315, H319
References & Citations
[1]Parsons CG, et al. Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization. Journal of Pharmacology and Experimental Therapeutics (1997), 283 (3), 1264-1275
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

Chemical Information

8-Bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one
CAS Number202808-11-5
PubChem CID9801704
IUPAC Name8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one
Molecular FormulaC11H6BrN3O3
Molecular Weight308.09
XLogP2.7
Topological Polar Surface Area85.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Heavy Atom Count18
Formal Charge0
Complexity500
SMILES
C1=CC2=C(C=C1Br)C=C3C(=C(N=NC3=O)O)N2O
InChI
InChI=1S/C11H6BrN3O3/c12-6-1-2-8-5(3-6)4-7-9(15(8)18)11(17)14-13-10(7)16/h1-4,17-18H
InChIKey
AXFGZZXFEDISAJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 8-Bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one
CAS: 202808-11-5
CID: 9801704
Formula: C11H6BrN3O3
MW: 308.09
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight308.09
XLogP32.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass306.95925
Monoisotopic Mass306.95925
Topological Polar Surface Area85.5 Ų
Heavy Atom Count18
Formal Charge0
Complexity500
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-133059MRZ-8676
HY-13802-01SC-514
HY-167847IRI-514
HY-D2022ATTO 514
HY-D2030ATTO 514 streptavidin
HY-D2031ATTO 514 biotin
HY-D2028ATTO 514 maleimid
HY-D2032ATTO 514 amine
HY-D2033ATTO 514 azide
HY-13802RSC-514 (Standard)

Alternative Products

CatalogName
CIA80811-01MRZ 2/514
BUP12574-01MRZ 2-514
A20277-50MRZ 2-514 50mg
A20277-10MRZ 2-514 10mg
A20277-100MRZ 2-514 100mg
A20277-25MRZ 2-514 25mg
A20277-5MRZ 2-514 5mg
A20277-1MRZ 2-514 1mg
8B1199-AATDRP-2 (Ab-514) Antibody
TBI1054-50MGSC-514, IKK-2 inhibitor

Popular Products