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(+) -Eudesmin

CAT: 0804-HY-N2180-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N2180-01Size:1 mg
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Description
Pinoresinol dimethyl ether ((+) -Eudesmin) is a non-phenolic furanoid lignin. Pinoresinol dimethyl ether can be isolated from Magnolia biondii. Pinoresinol dimethyl ether activates MAPK, PKC, and PKA upstream pathways and inhibits NO levels. Pinoresinol dimethyl ether has neuroprotective activity[1][2][3].
CAS Number
[29106-36-3]
Product Name Alternative
(+) -Eudesmine
UNSPSC
12352005
Hazard Statement
H302
Target
NO Synthase; p38 MAPK; PKA; PKC
Type
Natural Products
Related Pathways
Epigenetics; Immunology/Inflammation; MAPK/ERK Pathway; Stem Cell/Wnt; TGF-beta/Smad
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pinoresinol-dimethyl-ether.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC=C([C@H]2OC[C@]3([H])[C@@H](C4=CC=C(OC)C(OC)=C4)OC[C@@]32[H])C=C1OC
Molecular Formula
C22H26O6
Molecular Weight
386.44
Precautions
H302
References & Citations
[1]TeruhisaMiyauchi, et al. Formation of (+) -eudesmin in Magnolia kobus DC. Var. borealis sarg. Phytochemistry, 1998, 47 (4) : 665-670.|[2]Yang YJ, et al. Effects of (+) -eudesmin from the stem bark of magnolia kobus DC. var. borealis Sarg. on neurite outgrowth in PC12 cells. Arch Pharm Res. 2006 Dec;29 (12) :1114-8.|[3]Demiryürek AN, et al. Protective effects of verbenalin and (+) -eudesmin against 6-hydroxydopamine-induced oxidative/nitrosative stress in SH-SY5Y cells. Mol Biol Rep. 2023 Jan;50 (1) :331-338.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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