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β-Eudesmol

CAT: 0804-HY-N6018-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N6018-01Size:1 mg
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Description
β-Eudesmol has anticancer and anti-inflammatory activities. Beta-Eudesmol can induce apoptosis. β-Eudesmol is a neostigmine antagonist. β-Eudesmol can antagonize neostigmine-induced neuromuscular failure. β-Eudesmoll can be used in the study of sepsis diseases. β-Eudesmol is a sesquiterpene-like compound that can be extracted from the rhizome of Atractylodes lancea[1][2][3][4].
CAS Number
[473-15-4]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Caspase; Reactive Oxygen Species (ROS) ; SOD; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/beta-eudesmol.html
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
C[C@]12[C@@](C(CCC2)=C)([H])C[C@H](C(C)(O)C)CC1
Molecular Formula
C15H26O
Molecular Weight
222.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Ma EL, et al. Beta-eudesmol suppresses tumour growth through inhibition of tumour neovascularisation and tumour cell proliferation. J Asian Nat Prod Res. 2008 Jan-Feb;10 (1-2) :159-67.|[2] Xu Q, et al. Protective effects of β-eudesmol against septic liver injury via inhibition of NF-κB signaling[J]. Tropical Journal of Pharmaceutical Research, 2022, 21 (6) : 1183-1188.|[3]Chiou LC, et al. Antagonism by beta-eudesmol of neostigmine-induced neuromuscular failure in mouse diaphragms. Eur J Pharmacol. 1992 Jun 5;216 (2) :199-206.|[4]Hoang D M, et al. Eudesmols induce apoptosis through release of cytochrome c in HL-60 cells[J]. Natural Product Sciences, 2010, 16 (2) : 88-92.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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