C5 Lenalidomide

• Product Name Alternative:

  Lenalidomide 5'-amine

• UNSPSC Description:

  C5 Lenalidomide (Lenalidomide 5'-amine) is a thalidomide analog and is a potent inhibitor of TNF-alpha production (IC50=100 μM in LPS stimulated human PBMC)[1].

• Target Antigen:

  TNF Receptor

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/c5-lenalidomide.html

• Purity:

  99.62

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(C(N(CC1=C2C=CC(N)=C1)C2=O)CC3)NC3=O

• Molecular Weight:

  259.26

• References & Citations:

  [1]G W Muller, et al. Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1625-30.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  191732-70-4