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Triptolide

CAT: 1568-C09448-1gSize: 1 gDry Ice: YesHazardous: No
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CAT#:1568-C09448-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
38748-32-2
Synonyms
PG490, NSC 163062
Target
NF-κB
Applications
NF-κB
Molecular Formula
C20H24O6
Additionnal Information
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1) . Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.
Storage Conditions
2 years -80 in solvent

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