Triptolide-6-β-D-glucose

• Description:

  Triptolide-6-β-D-glucose (Compound 5) is a glucose-conjugated derivative of Triptolide (HY-32735) . Triptolide-6-β-D-glucose has no effective anti-tumor activity and is mainly used for studying the structural-activity relationship (SAR) of derivatives[1].

• UNSPSC:

  12352005

• Target:

  Drug Derivative

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Smiles:

  OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1O[C@@H]2[C@@]3(C(C)C)O[C@@]([C@@]4(O[C@]45[C@@]62O[C@@](C[C@]7(C(CO8)=C(CC[C@@]75C)C8=O)[H])6[H])[H])3[H]

• Molecular Formula:

  C26H34O11

• Molecular Weight:

  522.54

• References & Citations:

  [1]He QL, et al. Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation. Angew Chem Int Ed Engl. 2016 Sep 19;55 (39) :12035-9. doi: 10.1002/anie.201606121

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2003231-32-9