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ML218

CAT: 1568-C04744-1mgSize: 1 mgDry Ice: NoHazardous: No
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CAT#:1568-C04744-1mgSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1346233-68-8
Target
Calcium Channel
Applications
Neuronal Signaling
Molecular Formula
C19H26Cl2N2O
Additionnal Information
ML218 is a potent, selective, and orally active inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, and Cav3.3), with IC50 of 310 nM for Cav3.2 and 270 nM for Cav3.3. It effectively suppresses burst activity in subthalamic nucleus (STN) neurons.