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THZ1

CAT: 1568-C01928-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C01928-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1604810-83-4
Target
CDK
Applications
Cell Cycle
Molecular Formula
C31H28ClN7O2
Additionnal Information
THZ1 is a potent and covalent inhibitor of CDK7 with an IC50 of 3.2 nM. It also inhibits the CDK12 and CDK13 and downregulates MYC expression. It exhibits strong anti proliferative effect across a broad range of cancer cell lines including human T-cell acute lymphoblastic leukaemia (T-ALL) cancer.

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