Flavanone

CAT: 0804-HY-N7128-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N7128-01Size:100 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase) . Flavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy[1][2].
CAS Number
[487-26-3]
UNSPSC
12352005
Hazard Statement
H290, H314
Target
Cytochrome P450; ERK; MMP; NF-κB; p38 MAPK; PAI-1
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flavanone.html
Purity
99.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1CC(C2=CC=CC=C2)OC3=CC=CC=C13
Molecular Formula
C15H12O2
Molecular Weight
224.26
Precautions
H290, H314
References & Citations
[1]JT Kellis Jr, et al. Inhibition of human estrogen synthetase (aromatase) by flavones. Science. 1984 Sep. 225 (4666) :1032-1034.|[2]Hsiao YC, et al., Flavanone and 2'-OH flavanone inhibit metastasis of lung cancer cells via down-regulation of proteinases activities and MAPK pathway. Chem Biol Interact. 2007 May 1;167 (3) :193-206.|[3]Hsiao YC, et al., The tumor-growth inhibitory activity of flavanone and 2'-OH flavanone in vitro and in vivo through induction of cell cycle arrest and suppression of cyclins and CDKs. J Biomed Sci. 2007 Jan;14 (1) :107-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aromatase/CYP19A1

Related Products

CatalogName
HY-N14590Flagranone A
HY-N14592Flagranone C
HY-N14591Flagranone B
HY-N2424-01Flavone
HY-N2424R-01Flavone (Standard)
HY-N131877,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside
HY-N2657Flavone, 5,7-dihydroxy-3,4',8-trimethoxy-, diacetate
HY-N11488-015,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb
HY-N129595,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone
HY-N136003,5,8,3'-Tetramethoxy-6,7,4',5'-bis (methylenedioxy) flavone

Alternative Products

CatalogName
M14638-01Flavanone
sc-496295Flavanone-d5
MBS5766659Flavanone hydrazone
F01410-01Flavanone 98%
MBS7194221Flavonol synthase/flavanone 3-hydroxylase Antibody
MBS1372999-01Recombinant Petroselinum crispum Flavanone 3-dioxygenase (FHT)
MBS1363171-01Recombinant Solanum tuberosum Flavonol synthase/flavanone 3-hydroxylase
MBS1070786-01Recombinant Matthiola incana Flavonol synthase/flavanone 3-hydroxylase
AP77586-01Recombinant Arabidopsis thaliana Flavonol synthase/flavanone 3-hydroxylase(FLS1)
CSB-EP842601DOA-01Recombinant Arabidopsis thaliana Flavonol synthase/flavanone 3-hydroxylase (FLS1)

Popular Products