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MICROVUETMFactor I EIA

CAT: 1008-A041Size: 96 wells/testDry Ice: NoHazardous: No
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CAT#:1008-A041Size:96 wells/test
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Factor I (FI) is a negative regulatory protein of the complement system, and inhibits all pathways by cleaving activation components C4b and C3b. FI is a soluble protein, and circulates freely in the blood, though in an inactive state. Once FI is in the presence of a variety of co-factors it activates and inhibits complement activation. These co-factors include Factor H (only for C3b cleavage), MCP (CD46), CD35, and C4BP. The MICROVUE Factor I EIA measures the concentration of Factor I in serum or plasma. It uses a monoclonal antibody to Factor I, which is subsequently detected with an HRP-conjugated antibody that bind to another epitope of Factor I. This test, which provides a rapid, highly specific and quantitative procedure for measuring Factor I levels, is designed for investigations studying the role or status of complement pathway regulation in numerous research settings.
Description
The MICROVUE Factor I EIA is an enzyme immunoassay for the quantitative measurement of complment Factor I.
Cross Reactivity
None
Assay Performance Time
2.5 hours
Standard
5
Sample Type
Serum/EDTA Plasma 10 μL
Sample Volume
None
Limit Of Detection
0.5 ng/mL
Form
96 well plate with 12 eight-well strips in a resealable foil pouch
Storage Conditions
Store the unopened kit at 2°C to 8°C. Refer to Product Insert for additional storage details.
Limit Of Quantification
82.1 ng/mL
Controls
2
Inter Assay
5%
Intra Assay
3%

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