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C4a Antibody (Polyclonal)

CAT: 1008-A316Size: 1.0 mLDry Ice: NoHazardous: No
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CAT#:1008-A316Size:1.0 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Under normal conditions, activation of the classical or lectin complement pathways results in the cleavage of the complement protein, C4 into C4a and C4b by the protease C1s. C4a is rapidly cleaved to its more stable, less active form C4a-des Arg by endogenous serum carboxypeptidase N enzyme. Thus, detection of C4a-des Arg provides a reliable evaluation of classical or lectin complement pathway activation.
Description
A rabbit antiserum raised against human complement C4a protein.
Cross Reactivity
Human
Immunogen
Highly purified human C4a
Clonality
Polyclonal
Source
Rabbit
Applications
See citations and technical data sheet for application info.
Concentration
> 40 mg/mL
Form
Liquid. Whole Antiserum. ≤ 0.1% Sodium Azide
Storage Conditions
Short term (30 days) 4 ̊C. Long term at or below –20 ̊C.
Specificity
The Anti-Human C4a polyclonal antisera was tested by immunodiffusion methods and determinded to be monospecific for the C4a protein.
Isotype
Rabbit IgG
Conjugate
Unconjugated

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