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Regorafenib Hydrochloride

CAT: 0957-S4947-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-S4947-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
835621-07-3
Synonyms
Stivarga, BAY 73-4506 hydrochloride
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
Cl.CNC (=O) C1=NC=CC (=C1) OC2=CC (=C (NC (=O) NC3=CC (=C (Cl) C=C3) C (F) (F) F) C=C2) F
Molecular Formula
C21H16Cl2F4N4O3
Additionnal Information
Regorafenib (Stivarga, BAY 73-4506) Hydrochloride is a multi-target inhibitor for VEGFR1, Murine VEGFR2/3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM, 4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.
Storage Conditions
3 years -20°C powder