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Regorafenib

CAT: 0957-S1178-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1178-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy.
CAS Number
755037-03-7
Synonyms
Fluoro-Sorafenib, BAY 73-4506
Target
C-RET
Activity
Protein Tyrosine Kinase
Molecular Formula
C21H15ClF4N4O3
Storage Conditions
2 years -80 in solvent

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