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Mardepodect

CAT: 0957-E7654-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E7654-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
898562-94-2
Synonyms
PF-2545920
Target
PDE
Applications
Metabolism
Molecular Formula
C25H20N4O
Additionnal Information
Mardepodect is a potent, orally active, and selective inhibitor of PDE10A with an IC50 of 0.37 nM and >1000-fold selectivity over other phosphodiesterases. It also suppresses microglial activation in LPS-induced neuroinflammation and MPTP-induced Parkinson's disease mouse models.

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