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Mardepodect hydrochloride

CAT: 0931-T62356-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T62356-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2070014-78-5
Target
Apoptosis, PDE
Related Pathways
Apoptosis, Metabolism
Purity
0.951
Bioactivity
Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM) .Mardepodect hydrochloride up-regulates the expression of proteins encoding specific growth and transcription factors, cell signalling molecules and cell surface proteins. Mardepodect hydrochloride upregulates genes encoding specific growth factors, transcription factors, cell signalling molecules, and cell surface proteins, while downregulating a broad spectrum of cell cycle and apoptosis-related genes.
Smiles
Cl.Cn1cc(c(n1)-c1ccc(OCc2ccc3ccccc3n2)cc1)-c1ccncc1
Molecular Formula
C25H21ClN4O
Molecular Weight
428.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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