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I-138

CAT: 0957-E1479-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-E1479-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2098211-50-6
Target
DUB
Applications
Ubiquitin
Molecular Formula
C26H23F3N6O
Additionnal Information
I-138 is an orally active, potent reversible inhibitor of USP1-UAF1 with IC50 0f 4.1 nM. I-138 is structurally related to ML323 and induces the monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells and increases PCNA and FANCD2 monoubiquitination in HAP-1 USP1 WT cells.

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BA3896-10I-138
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ARC1029Z-138

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