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Nitroxoline (Standard)

CAT: 0804-HY-B1159R-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1159R-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nitroxoline (Standard) is the analytical standard of Nitroxoline. This product is intended for research and analytical applications. Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research[1][2][3].
CAS Number
4008-48-4
Product Name Alternative
8-Hydroxy-5-nitroquinoline (Standard) ; 5-Nitro-8-quinolinol (Standard)
UNSPSC
12352005
Target
Antibiotic; Apoptosis; Autophagy; Bacterial; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Autophagy; Others
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/nitroxoline-standard.html
Smiles
OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1
Molecular Formula
C9H6N2O3
Molecular Weight
190.16
References & Citations
[1]Jin-Guo Yu, et al. Nitroxoline induces cell apoptosis by inducing MDM2 degradation in small-cell lung cancer. Kaohsiung J Med Sci. 2019 Apr;35 (4) :202-208. |[2]A Sobke, et al. The urinary antibiotic 5-nitro-8-hydroxyquinoline (Nitroxoline) reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Antimicrob Agents Chemother. 2012 Nov;56 (11) :6021-5.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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