DBCO-PEG4-C2-acid

• UNSPSC Description:

  DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-C2-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dbco-peg4-c2-acid.html

• Purity:

  99.22

• Solubility:

  DMSO : 41.67 mg/mL (ultrasonic)

• Smiles:

  O=C(O)CCOCCOCCOCCOCCNC(CCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)=O

• Molecular Weight:

  552.62

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1537170-85-6