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Droxinostat

CAT: 1568-C16306-02Size: 10 mgDry Ice: YesHazardous: No
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CAT#:1568-C16306-02Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
99873-43-5
Synonyms
NS 41080
SKU
C16306-10mg
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CC1=C (C=CC (=C1) Cl) OCCCC (=O) NO
Molecular Formula
C11H14ClNO3
Additionnal Information
Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
Storage Conditions
2 years -80 in solvent

Chemical Information

4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide

4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide is an aromatic ether.

CAS Number99873-43-5
PubChem CID568416
IUPAC Name4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide
Molecular FormulaC11H14ClNO3
Molecular Weight243.68
XLogP2.8
Topological Polar Surface Area58.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Heavy Atom Count16
Formal Charge0
Complexity225
SMILES
CC1=C(C=CC(=C1)Cl)OCCCC(=O)NO
InChI
InChI=1S/C11H14ClNO3/c1-8-7-9(12)4-5-10(8)16-6-2-3-11(14)13-15/h4-5,7,15H,2-3,6H2,1H3,(H,13,14)
InChIKey
JHSXDAWGLCZYSM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
CAS: 99873-43-5
CID: 568416
Formula: C11H14ClNO3
MW: 243.68
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight243.68
XLogP32.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass243.0662210
Monoisotopic Mass243.0662210
Topological Polar Surface Area58.6 Ų
Heavy Atom Count16
Formal Charge0
Complexity225
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-13267-01Droxinostat

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