Ceritinib

• CAS Number :

  1032900-25-6

• Synonyms :

  LDK378

• SKU :

  C12426-5mg

• Target :

  ALK

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  CC1=CC (=C (C=C1C2CCNCC2) OC (C) C) NC3=NC=C (C (=N3) NC4=CC=CC=C4S (=O) (=O) C (C) C) Cl

• Molecular Formula :

  C28H36ClN5O3S

• Additionnal Information :

  Ceritinib is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays. Ceritinib (LDK378) also inhibits IGF-1R, InsR, STK22D and FLT3 with IC50 of 8 nM, 7 nM, 23 nM and 60 nM, respectively. Phase 3.

• Storage Conditions :

  2 years -80 in solvent